The biggest disadvantage of the TRAXX 2E was that electric and diesel variants could not be built with the same locomotive body. This resulted in the further developed generation 2E, in which there is an installation field for the power converter or diesel generator in the middle of the locomotive body. Only a multi-system and a pure DC variant were created. The latter is also used in broad gauge in Spain. The multi-system variant is used by a large number of operators in large parts of Europe. Depending on the country, a maximum speed of 160 km/h is possible with the further developed nose-suspended motors. The diesel variants are described in a separate article. 